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Tyrone B Hayes Selected Research

Atrazine

10/2011Demasculinization and feminization of male gonads by atrazine: consistent effects across vertebrate classes.
3/2010Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis).
5/2007Atrazine-induced aromatase expression is SF-1 dependent: implications for endocrine disruption in wildlife and reproductive cancers in humans.
4/2006Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis.
4/2002Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses.

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Tyrone B Hayes Research Topics

Disease

3Feminization
10/2011 - 04/2006
2Disorders of Sex Development (Intersexuality)
04/2006 - 04/2002
1Carcinoma (Carcinomatosis)
05/2007
1Neoplasms (Cancer)
05/2007
1Prostatic Neoplasms (Prostate Cancer)
05/2007
1Meningitis
04/2006

Drug/Important Bio-Agent (IBA)

5AtrazineIBA
10/2011 - 04/2002
1Endocrine DisruptorsIBA
05/2007
1Aromatase (CYP19)IBA
05/2007
1Cyproterone AcetateIBA
04/2006
1PesticidesIBA
04/2006
1Androgen Antagonists (Antiandrogens)IBA
04/2006
1AndrogensIBA
04/2006
1Estrogens (Estrogen)FDA Link
04/2006
1Estradiol (Delestrogen)FDA LinkGeneric
04/2006

Therapy/Procedure

2Castration
03/2010 - 04/2006